• February 24 – 32nd Annual Spirit of Keokuk Awards
• March 25 – Downtown Quarterly Clean-Up
• May 6 – First Friday
• May 27 – 16th Annual Back Alley Bandfest
• June 3 – First Friday
• June 18 – Downtown Quarterly Clean-up
• July 1 – First Friday
• July 9 – 22nd Annual Summer Fun & Fundraiser
• July 21-23 65th Annual Crazy Days
• August 5 – First Friday
• September 2 – First Friday
• October 7 – First Friday
• October 22 – Downtown Quarterly Clean-Up
• October 28 – Downtown Trick or Treat
• November 4 – First Friday
• November 28 – Small Business Saturday
• December 2 – Puttin’ On the Glitz
• December 10 – Santa’s Workshop

If you have any questions about events happening in 2022, please call the MSKI office at (319)524-5056 or email director@mainstreetkeokuk.com